distillation №14

— — —

—PERFORMANCEMay 2, 2026[ FAILED ]

[↓ download report.pdf]

average confidence

—

pTM

—

ipTM

—

binding Δ

—

agreement

—

target

—

uniprot

—

01/

3D structure

// no structure on file

pdb file not produced for this fold

// powered by Mol* — drag to rotate · scroll to zoom · use the right panel for cartoon / spacefill / surface presets, measurements & export

chain A — peptide (plasma red)chain B+ — target / context (white)

02/

AI analysis

tldr

—

detailed analysis

—

03/

research data

known activity

// not yet provided by clinical agent

biohacker use

// not yet provided by clinical agent

mechanism class

// not yet provided by clinical agent

05/

folding metrics

// no per-residue pLDDT trace — Boltz-2 returned summary metrics only

confidence metrics

pLDDT mean

0.00

pTM

—

ipTM

—

Boltz ↔ Chai

—

06/

domain annotations

// not yet annotated by clinical / structural agents

08/

peptide profile

These are sequence-based heuristic estimates, not wet-lab measurements. Real aggregation propensity requires TANGO/Aggrescan, real BBB permeability requires QSAR models, and real half-life requires PK studies. Treat the numbers as ranked indicators — useful for comparing variants, not for absolute claims.

aggregation propensity

heuristic

—

● —

Predicted likelihood of self-aggregation. Lower is better.

≤ 0.40 good · ≤ 0.80 moderate

source: Kyte-Doolittle window proxy

stability prediction

heuristic

—

● —

Composite stability score. Higher = more stable in solution.

≥ 0.70 good · ≥ 0.40 moderate

source: charge / proline / length composite

BBB penetration

heuristic

—

● —

Estimated blood-brain barrier permeability. Goal depends on target tissue.

≥ 0.50 high · ≥ 0.20 moderate

source: hydrophobic fraction proxy

half-life estimate

heuristic

—

● —

In-silico estimated plasma half-life range.

text estimate

source: length-bucket heuristic

09/

known binders

// no ChEMBL binders found for this target

11/

agent findings

1 findingslast updated: 2026-05-02 21:32:20 UTC

researcher: 1

☿RESEARCHER agentclaude-opus-4-7

2026-05-02 21:32:04 UTC· 15.5s● FAILED

// no summary recorded

12/

caveats

─in silico prediction only — requires wet lab validation
─single-run prediction (not ensembled)
─predicted properties may not reflect biological reality
─this is research, not medical advice
─modified peptides have not been synthesized or tested

13/

data

[↓ download fold.json][no pdb available][⊘ on-chain unavailable][⎘ copy permalink]